A comparison of bone-targeted exercise strategies to reduce fracture risk in middle-aged and older men with osteopenia and osteoporosis: LIFTMOR-M semi-randomized controlled trial

Review written by Dr Mariana Wingood info

Key Points

  1. LIFTMOR is an 8-month supervised high-intensity resistance and impact training (HiRIT) program that has been identified to improve femoral neck and lumbar spine BMD, muscle strength, and physical function.
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BACKGROUND & OBJECTIVE

While osteoporotic fractures among individuals 50 years and older are more common in women (1 in 3) compared to men (1 in 5), men’s fragility fracture is associated with higher morbidity and mortality (1). Exercise is a primary modifiable factor capable of influencing bone health by preserving bone mass and strength (2,3). The primary ability of exercise to prevent fractures is through a reduction in falls. According to a recent Cochrane review, exercise reduces the rate of falls in older adults by 23%, and the number of individuals experiencing fractures by 27% (4). The type of exercise that has seen the greatest amount of recognition is high intensity exercise.

One example of this is the Training Muscle and Osteoporosis Rehabilitation (LIFTMOR), which is an 8-month supervised high-intensity progressive resistance and impact training (HiRIT) program that has been identified to improve femoral neck and lumbar spine bone mass density (BMD), muscle strength, and physical function in postmenopausal women with low to very low bone mass (5,6). Since the initial study was done on women, the authors of this study wanted to examine the impact of participating in LIFTMOR in men (LIFTMOR-M).

The primary ability of exercise to prevent fractures in older adults is through a reduction in falls.
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By incorporating a bi-weekly high intensity exercise program with your patients, this may improve their bone mass density at the proximal femur and lumbar spine.

METHODS

Participants: Healthy men who were 45+ years and had osteopenia or osteoporosis at the lumbar spine and/or proximal femur (determined by DXA). Participants were excluded if they had a condition likely to affect the ability to exercise; recent fracture or

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