How does hip osteoarthritis differ from knee osteoarthritis?

Key Points

1. This review highlighted differences between hip and knee osteoarthritis (OA) with respect to prevalence, prognosis, epigenetics, pathophysiology, anatomical and biomechanical factors, clinical presentation, pain, and clinical practice recommendations and current practice.

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BACKGROUND & OBJECTIVE

Hip and knee osteoarthritis (OA) are leading causes of global disability (1). Most research to date has focused on knee OA or mixed populations of hip and knee OA. The results of these studies have often been generalized to people with hip OA, including treatment recommendations in clinical guidelines (2,3).

Therefore, the purpose of this review was to highlight potential differences between hip OA and knee OA, with the goal of better understanding disease characteristics specific to hip OA and potentially informing the development and implementation of effective treatments for this patient population.

Studies on knee OA have often been generalized to people with hip OA, including treatment recommendations in clinical guidelines.

Biomechanical interventions, such as wedges and gait retraining, may be less relevant for people with hip OA compared to knee OA.

METHODS

The authors conducted a narrative review of the available scientific literature on articles directly comparing hip OA and knee OA. Evidence from systematic reviews and meta-analyses on people with hip and/or knee OA was also included. For topics not addressed

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